Gen 3:15 is
often taken as a Messianic prophecy. While many modern Jews reject this
reading, some Jewish texts interpreted it in a Messianic fashion. One such text
is Targum Neofiti which renders the verse as follow:
And I will put enmity between you" and
the woman and between your sons' and her sons. And it will come about that
when her sons observe the Law and do the commandments they will aim at you and
smite you on your head and kill you. But when they forsake the
commandments of the Law you will aim and bite him on his heel and
make him ill. For her sons, however, there will be a remedy, but
for you, O serpent, there will not be a remedy, since they are to make
appeasement in the end, in the day of King Messiah. (Targum Neofiti 1: Genesis [The Aramaic Bible volume 1A; trans.
Martin McNamara; Collegeville, Minn.: The Liturgical Press, 1992], 61, italics
in original)